Director, DMPK

Job Description

Watton Hall are working with a leading biotechnology firm focused on developing innovative therapies to address unmet medical needs. There mission is to improve patient outcomes through cutting-edge research and development in the pharmaceutical industry.

The Director of DMPK will provide strategic leadership and scientific expertise in drug metabolism, pharmacokinetics (PK), and pharmacodynamics (PD) for our drug discovery and development programs. This role requires collaboration with cross-functional teams to ensure the successful advancement of small molecule candidates from preclinical through clinical stages.

Main Responsibilities

• Develop and implement DMPK strategies that align with project goals, ensuring timely selection and progression of drug candidates.
• Work closely with medicinal chemistry, toxicology, clinical operations, and regulatory affairs teams to support integrated drug development efforts.
• Prepare and review DMPK-related sections for regulatory submissions such as INDs, NDAs, and BLAs; and respond to regulatory enquiries.
• Manage partnerships with contract research organizations (CROs) to ensure timely execution of studies while maintaining high-quality standards.
• Lead a team of scientists by providing mentorship, fostering professional growth, and promoting a culture of innovation.

Profile

• PhD in Pharmacology, Drug Metabolism (or a related field)
• Experience with regulatory requirements for drug submissions is essential.
• Proven track record in designing and conducting PK studies supporting small molecule drug development
• Excellent communication skills with the ability to work collaboratively in a fast-paced environment.

Benefits

• Competitive salary commensurate with experience along with performance-based bonuses and comprehensive benefits package
• Home office option
• Excellent company culture
• Exposure to a dynamic and evolving Biotech company

Originally posted on Himalayas